Product descriptions

Topiramate is a drug used for epilepsy or migraines, but it has recently been in the spotlight as a diet drug due to side effects of weight loss in patients who used the drug.

Topiramate is a type of drug that lowers appetite and increases energy metabolism, which promotes thermogenesis and reduces food intake. It is said to have the effect of losing weight.

Topiramate is also included among the main ingredients of Qsimia*, which is well known as an appetite suppressor.

According to a clinical trial conducted on migraine patients, a 13.6 kg drop was confirmed within four months of taking topiramate. Starting with a small dose and slowly increasing the dose can reduce the risk of side effects. 

Effect/Effectiveness

Topiramate is responsible for inhibiting the stimulation of GABA (γ-amino-butyric-acid) receptors, inhibiting the stimulation of the brain, inhibiting the Na+ channel, inhibiting the secretion of glutamate, and inhibiting the synthesis of substances that induce the stimulation of the brain. In other words, it prevents and treats epilepsy by suppressing the stimulation of the brain.

This mechanism helps relieve migraine symptoms by lowering brain sensitivity and can be expected to have effects such as bulimia and weight loss.

According to a study by Dr. Silverstein, director of the Headache Center at Jefferson University in the United States, patients taking Topamax for headaches lost an average of 30 pounds (13.6 kilograms) over four months, and even when Topamax was administered for a year for epilepsy treatment, it showed a weight loss effect of 11-12%. 

How to take it

For epilepsy patients, it is recommended to take 100 to 200 mg per day as an adult.

It can be taken up to 500mg, but it can be increased according to the doctor's judgment.

As an additional therapy for adults, the minimum effective dose is 200 mg per day, and usually 200 to 400 mg per day is divided, and depending on the patient, up to 800 mg per day can be administered.

If it is taken for the purpose of preventing migraines, it is recommended to take 100 mg per day for adults and should be divided into two doses.

If you take it for diet purposes, it is recommended to take 25mg to 50mg per day. 

Precautions for use

It is recommended not to administer it to patients with arteriosclerosis, cardiovascular disease, and moderate or higher hypertension because there is a risk of raising blood pressure. You should be careful about driving and operating the machine because you may feel sleepy after taking it.

In the case of diabetic patients, if there is a drug you have been taking, you should decide whether to take it or not after consulting with a specialist.

It inhibits the effectiveness of contraceptives, so you should take them with this in mind. 

Side effects

In general, none of the side effects of topiramate are known to be serious, but the typical known side effects include numbness in the hands, drowsiness, memory and concentration. 

These symptoms disappear within a few days or if you stop taking medicine, but if the symptoms continue, you should take measures such as continuing taking them and controlling the dose through the medical staff.

Manufacturer/ingredient

Healing Pharma India Pvt. Ltd.

Topiramate 100mg