Ingredients/Content

Active ingredients: 1 tablet Apremilast 30mg

What is psoriasis arthritis?

The cause of psoriasis can be found in the cause of psoriasis. Psoriasis is an autoimmune disease that occurs due to abnormal immune systems, and skin cells proliferate faster than normal due to excessive inflammatory reactions. Psoriasis arthritis occurs when cells or cytokines that cause these inflammatory reactions increase in the joint. Environmental factors such as eye infection and trauma and genetic factors are also known to be involved in the etiology of psoriasis arthritis in addition to immunological factors

Symptoms of psoriasis arthritis

Psoriasis arthritis is inflammatory arthritis that invades ligaments, tendons, fascia, vertebrae and peripheral joints, where rheumatoid factors are negative and often accompanied by nail lesions, and in addition to arthritis, osteoarthritis of the bone attachment area of the ligament is showing inflammation, and the fingers are swollen due to inflammation, which can also be found in the form of a sausage. Clinically, it can be divided into five types (symmetric multiple arthritis, asymmetric hydrophobic arthritis, malignancy arthritis, disconnected arthritis, and spondylitis) depending on the severity of the disease.

In particular, psoriasis arthritis is important to distinguish it from rheumatoid arthritis, which tends to be asymmetric and has fewer intrusive joints than rheumatoid arthritis, and mainly affects terminal joints. Along with nail lesions, osteo-adhesive inflammation and ankylitis are more common than rheumatoid arthritis, and spinal arthritis is also observed in 20-30% of psoriasis arthritis. In addition, rheumatoid arthritis is more common in women, while psoriasis arthritis is different from rheumatoid arthritis because there is no difference between men and women, and most of them have negative rheumatoid factors.

Efficacy/Effectiveness

Apremilast is a phosphodiesterase 4 (PDE4) inhibitor and acts to reduce PDE4 activity within inflammatory cells. It is thought that the decrease in PDE4 activity helps to reduce irritable inflammation that occurs in patients with plaque psoriasis. Less inflammation can reduce the symptoms of plaque psoriasis. In other words, redness, thickness, and scale of plaque may be small. 

Packaging unit

60 tablets

Storage method

Store at room temperature (1-30℃), shielded airtight container

Manufacturer

Glenmark (Onkos) Pharmaceuticals Ltd.

etc

We encourage you to consult with your doctor before your personal income to gain sufficient knowledge of your medicines.